The Great Smoky Mountains are a mountain range rising along the Tennessee–North Carolina border in the southeastern United States. They are a part of the Appalachian Mountains, and form part of the Blue Ridge Physiographic Province. The range is sometimes called the “Smoky Mountains” and the name is commonly shortened to the “Smokies.” The Great Smokies are best known as the home of the Great Smoky Mountains National Park, which protects most of the range. The park was established in 1934, and, with over 9 million visits per year, it is the most-visited national park in the United States.

The name "Smoky" comes from the natural fog that often hangs over the range and presents as large smoke plumes from a distance. This fog is caused by the vegetation exhaling volatile organic compounds, chemicals that have a high vapor pressure and easily form vapors at normal temperature and pressure.